The Alpha-Tubulin Conjugated Antibody from MyBioSource.com is a Mouse Monoclonal antibody to TUBA4A, and tubulin alpha 4a. This antibody recognizes Human, Mouse, Rat, and Zebrafish/Fish antigen. The Alpha-Tubulin Conjugated Antibody has been validated for the following applications: Other.
Description
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with alpha/beta-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. Acetylation of alpha chains at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling